Grants have been awarded to the University of Edinburgh to investigate a life-limiting neurological condition so that it can be better understood.
The condition, Progressive Supranuclear Palsy,(PSP) is rare and results from a loss of neurone in certain parts of the brain. The disease affects balance and mobility, as well as other senses such as speech and vision. A misdiagnosis can be common due to similarities with other diseases such as Parkinson’s.
Two researchers at the UK Dementia Research Institute at the University of Edinburgh, Dr Dianne Lopez, and Dr Filipa Henderson Sousa, have been given funding by The PSP Association (PSPA) for their studies.
Dr Lopez will investigate astrocytes, which are brain “support” cells in finding ways of slowing the disease. Dr Henderson Sousa will investigate the effect of PSP on protein in cells, with a view to finding early warning signs and targets for new drugs. There is currently no treatment or cure for the disease.
James Cusack, PSPA Chief Executive, explains “Thanks to the generosity of our supporters, our research appeal raised more than £1 million. As a result, we are proud to fund seven additional research studies helping to uncover the mysteries of PSP & CBD (Corticobasal Degeneration).
“Research really is the gatekeeper to progression in this area. Over the past ten years, it has helped us to understand the conditions much more. We’re excited for the studies led by Dr Lopez and Dr Henderson Sousa to begin in the New Year and look forward to learning out the outcomes achieved.”
Dr Sousa was also just awarded a 2025 Mentorship Prize by the UK Dementia Research Institute along with Paul Morgan of Cardiff University. This new mentoring award “acknowledges and rewards outstanding mentoring that fosters the growth, skills enhancement, and career progression of researchers within the institute”.
